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| No. | Article Type | Article Title | Article Page |
|---|---|---|---|
| 1 | Clinical Research | Recommendation for Clinical T Staging in Patients with Non-Small Cell Lung Cancer: Volumetric Measurement: A Retrospective Study from Turkey | 51 - 57 |
| 2 | Commentary | Commentary: Volumetry for Lung Nodule Assessment | 58 - 59 |
| 3 | Case Report | Sternal Reconstruction with Titanium Prosthesis for Complicated Sternal Dehiscence with Right Ventricle Herniation after Cardiac Surgery: A Case Report | 60 - 64 |
| 4 | How-to-do-it | Balloon and Glue Technique: A Modification of Distal Reinforcement to Prevent Anastomotic New Entry, Reducing Replacement Range in Acute Type A Aortic Dissection | 65 - 69 |
| 5 | Commentary | Commentary: The Balloon and Glue Technique in Acute Type A Aortic Dissection: Considerations for Optimization and Clinical Application | 70 - 72 |
| 6 | Historical Note | Historical Perspectives of the Korean Society for Thoracic and Cardiovascular Surgery: Sung Nok Hong (1927–2017) Who Performed the First Coronary Artery Bypass Graft in Korea | 73 - 76 |
| 7 | Correction | Correction: Commentary: Is the Data Strong Enough to Prorocolize the Approach in Diaphragmatic Hernia Repair? Aspects of Technique and the Sample Size of a Longitudinal Single-Center Study | 77 - 77 |
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Korean J Thorac Cardiovasc Surg 1998; 31(6): 560-566
Published online June 5, 1998
Copyright © Journal of Chest Surgery.
Jae Ho Ahn, M.D.I, Jae Jin Han, M.D.I, Sung Soo Park, M.D.II
IDepartment of Thoracic & Cardiovascular Surgery, Medical College, Ewha Women's University , IIDepartment of Anatomy Medical College, Ewha Women's University
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Bovine pericardial bioprosthesis treated with glutaraldehyde (GA) is one of the most popular prosthetic materials, but late calcific degeneration after implantation is a problem that remains unsolved. For the purpose of mitigating the calcific degeneration, we added MgCl2 into the 0.625% GA solution to compete with calcium for binding to the free aldehyde from GA and pretreated with the surfactants like sodium dodecyl sulfate (SDS) and Triton X-100 before GA fixation for preventing the phospholipid infiltration into the pericardial tissue, the first step of the calcific degeneration. Material and Method: 40 square-shaped pieces of bovine pericardia were fixed in 0.625% GA solution with 4g/L MgCl2 6H2O as a control group (group 1). 40 pieces pretreated with 1% SDS were also fixed in the same GA solution (group 2) and other 40 pieces pretreated with 1% Triton X-100 were prepared with the same method (group 3). After 1 month of fixation these were implanted into the belly of 40 Sprague-Dawley subdermally and extracted 1 month, 2 months, 3 months and 6 months after implantation. With atomic absorption spectrophotometry we measured the deposited calcium amount. Result: 1 month after implantation we could not find any differences between the three groups, but by the 2nd month calcium deposition was 0.921±0.121 mg/g in group 1, 0.481±0.037 mg/g in group 2 and 1.369±0.200 mg/g in group 3. By the 3rd month it was 0.786±0.080 mg/g in group 1, 0.584±0.054 mg/g in group 2 and 1.139±0.188 mg/g in group 3, and on the 6th month 1.623±0.601 mg/g in group 1,0.501±0.043 mg/g in group 2 and 1.625±0.382 mg/g in group 3, with statistical significance in group 2(p<0.05). Conclusion: Pretreatment with SDS showed meaningful
calcium mitigation effects on subcutaneously implanted bovine pericardium in the rat models but the neutral type surfactant, Triton X-100, had no positive mitigation effect in this experiment.
(Korean J Thorac Cardiovasc Surg 1998;31:560-6)
Keywords: Glutaraldehyde , Surfactant , Heterograft , Calcification
Korean J Thorac Cardiovasc Surg 1998; 31(6): 560-566
Published online June 5, 1998
Copyright © Journal of Chest Surgery.
Jae Ho Ahn, M.D.I, Jae Jin Han, M.D.I, Sung Soo Park, M.D.II
IDepartment of Thoracic & Cardiovascular Surgery, Medical College, Ewha Women's University , IIDepartment of Anatomy Medical College, Ewha Women's University
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Bovine pericardial bioprosthesis treated with glutaraldehyde (GA) is one of the most popular prosthetic materials, but late calcific degeneration after implantation is a problem that remains unsolved. For the purpose of mitigating the calcific degeneration, we added MgCl2 into the 0.625% GA solution to compete with calcium for binding to the free aldehyde from GA and pretreated with the surfactants like sodium dodecyl sulfate (SDS) and Triton X-100 before GA fixation for preventing the phospholipid infiltration into the pericardial tissue, the first step of the calcific degeneration. Material and Method: 40 square-shaped pieces of bovine pericardia were fixed in 0.625% GA solution with 4g/L MgCl2 6H2O as a control group (group 1). 40 pieces pretreated with 1% SDS were also fixed in the same GA solution (group 2) and other 40 pieces pretreated with 1% Triton X-100 were prepared with the same method (group 3). After 1 month of fixation these were implanted into the belly of 40 Sprague-Dawley subdermally and extracted 1 month, 2 months, 3 months and 6 months after implantation. With atomic absorption spectrophotometry we measured the deposited calcium amount. Result: 1 month after implantation we could not find any differences between the three groups, but by the 2nd month calcium deposition was 0.921±0.121 mg/g in group 1, 0.481±0.037 mg/g in group 2 and 1.369±0.200 mg/g in group 3. By the 3rd month it was 0.786±0.080 mg/g in group 1, 0.584±0.054 mg/g in group 2 and 1.139±0.188 mg/g in group 3, and on the 6th month 1.623±0.601 mg/g in group 1,0.501±0.043 mg/g in group 2 and 1.625±0.382 mg/g in group 3, with statistical significance in group 2(p<0.05). Conclusion: Pretreatment with SDS showed meaningful
calcium mitigation effects on subcutaneously implanted bovine pericardium in the rat models but the neutral type surfactant, Triton X-100, had no positive mitigation effect in this experiment.
(Korean J Thorac Cardiovasc Surg 1998;31:560-6)
Keywords: Glutaraldehyde , Surfactant , Heterograft , Calcification
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