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Korean J Thorac Cardiovasc Surg 2000; 33(10): 798-805

Published online October 5, 2000

Copyright © Journal of Chest Surgery.

Use of Quantitative CT to Predict Postoperative Lung Function (Comparison of Quantitative CT and Perfusion Lung Scan)

Jo Han Rhee, M.D.*, Seog-Jae Lee, M.D.*, Sung Jin Kim, M.D.**

*Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University, **Department of Radiology, College of Medicine, Chungbuk National University

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: The prediction on changes in the lung function after lung surgery would be an important indicator in terms of the operability and postoperative complications. In order to predict the postoperative FEV1 - the commonly used method for measuring changes in lung function - a comparison between the quantitative CT and the perfusion lung scan was made and proved its usefulness.
Material and Method: The subjects included 22 patients who received perfusion lung scan and quantitative CT preoperatively and with whom the follow-up of PFT were possibles out of the pool of patients who underwent right lobectomy or right pneumonectomy between June of 1997 and December of 1999. The FEV1 and FVC were calibrated by performing the PFT on each patient, and then the predicted FEV1 and FVC were calculated after performing perfusion lung scan and quantitative CT postoperatively. The FEV1 and FVC were calibrated by performing the PFT after 1 week and after 3 momths following the surgery.
Result: There was a significant mutual relationship between the predicted FEV1 and FVC using quantitative CT and perfusion lung scan and the actual postoperative FEV1 and FVC at 1 week and 3 months. The predicted FEV1 and FVC(pneumonectomy group : r=0.962 and r=0.938, lobectomy group : r=0.921 and r=913) using quantitative CT at 1 week postoperatively showed a higher mutual relationship than that predicted by perfusion lung scan(pneumonectomy group : r=0.927 and r=0.890, lobectomy group : r=0.910 and r=0.905). The result was likewise at 3 months postoperatively(CT - pneumonectomy group : r=0.827 and 0.921, lobectomy group : r=0.945 and r=0.935), (scan - pneumonectomy group : r=0.799 and r=0.882, lobectomy group : r=0.934 and r=0.932).
Conclusion: In comparison to perfusion lung scan, quantitative CT is more accurate in predicting lung function postoperatively and is cost-effective as well. Therefore, it can be concluded that the quantitative CT is an effective method of replacing the perfusion lung scan in predicting lung function post-operatively. However, it is noted that further comparative analysis using more date and follow-up studies of the patients is required.
(Korean Thorac Cardiovasc Surg 2000;33:798-805)

Keywords: Tomography, x-ray computed, Lung scan, Pulmonary function test

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Korean J Thorac Cardiovasc Surg 2000; 33(10): 798-805

Published online October 5, 2000

Copyright © Journal of Chest Surgery.

Use of Quantitative CT to Predict Postoperative Lung Function (Comparison of Quantitative CT and Perfusion Lung Scan)

Jo Han Rhee, M.D.*, Seog-Jae Lee, M.D.*, Sung Jin Kim, M.D.**

*Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University, **Department of Radiology, College of Medicine, Chungbuk National University

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: The prediction on changes in the lung function after lung surgery would be an important indicator in terms of the operability and postoperative complications. In order to predict the postoperative FEV1 - the commonly used method for measuring changes in lung function - a comparison between the quantitative CT and the perfusion lung scan was made and proved its usefulness.
Material and Method: The subjects included 22 patients who received perfusion lung scan and quantitative CT preoperatively and with whom the follow-up of PFT were possibles out of the pool of patients who underwent right lobectomy or right pneumonectomy between June of 1997 and December of 1999. The FEV1 and FVC were calibrated by performing the PFT on each patient, and then the predicted FEV1 and FVC were calculated after performing perfusion lung scan and quantitative CT postoperatively. The FEV1 and FVC were calibrated by performing the PFT after 1 week and after 3 momths following the surgery.
Result: There was a significant mutual relationship between the predicted FEV1 and FVC using quantitative CT and perfusion lung scan and the actual postoperative FEV1 and FVC at 1 week and 3 months. The predicted FEV1 and FVC(pneumonectomy group : r=0.962 and r=0.938, lobectomy group : r=0.921 and r=913) using quantitative CT at 1 week postoperatively showed a higher mutual relationship than that predicted by perfusion lung scan(pneumonectomy group : r=0.927 and r=0.890, lobectomy group : r=0.910 and r=0.905). The result was likewise at 3 months postoperatively(CT - pneumonectomy group : r=0.827 and 0.921, lobectomy group : r=0.945 and r=0.935), (scan - pneumonectomy group : r=0.799 and r=0.882, lobectomy group : r=0.934 and r=0.932).
Conclusion: In comparison to perfusion lung scan, quantitative CT is more accurate in predicting lung function postoperatively and is cost-effective as well. Therefore, it can be concluded that the quantitative CT is an effective method of replacing the perfusion lung scan in predicting lung function post-operatively. However, it is noted that further comparative analysis using more date and follow-up studies of the patients is required.
(Korean Thorac Cardiovasc Surg 2000;33:798-805)

Keywords: Tomography, x-ray computed, Lung scan, Pulmonary function test

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