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J Chest Surg

Published online November 9, 2022

Copyright © Journal of Chest Surgery.

Infected Left Atrial Myxoma Presenting Without Bacterial Growth on Blood Cultures: A Case Report

Shi A Kim, M.D. 1, WonKyung Pyo, M.D. 2, Sung-Ho Jung, M.D., Ph.D. 1

1Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine; 2Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea

Correspondence to:Sung-Ho Jung
Tel 82-2-3010-3580
Fax 82-2-3010-6966
E-mail csjung@amc.seoul.kr
ORCID
https://orcid.org/0000-0002-3699-0312

Received: July 18, 2022; Revised: September 29, 2022; Accepted: October 1, 2022

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although cardiac myxoma is one of the most common types of benign cardiac tumors, infected cardiac myxoma is very infrequent. The diagnosis of infected cardiac myxoma may be challenging because the presenting symptoms are non-specific and established management guidelines are lacking. This report describes a 39-year-old woman with a 5-month history of uncontrolled fever, chills, and myalgia who was diagnosed with myxoma and underwent mass excision. Although blood and urine cultures were negative for growing bacteria, a pathologic examination showed that the excised mass was a left atrial myxoma, with pan-bacterial polymerase chain reaction (PCR) of the surgical specimen revealing Haemophilus parainfluenzae at 99.87%, resulting in a diagnosis of infected cardiac myxoma. Laboratory tests, such as PCR, may supplement culture results in the diagnosis of infected cardiac myxoma.

Keywords: Infected cardiac myxoma, Haemophilus parainfluenzae, Case report

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J Chest Surg

Published online November 9, 2022

Copyright © Journal of Chest Surgery.

Infected Left Atrial Myxoma Presenting Without Bacterial Growth on Blood Cultures: A Case Report

Shi A Kim, M.D. 1, WonKyung Pyo, M.D. 2, Sung-Ho Jung, M.D., Ph.D. 1

1Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine; 2Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea

Correspondence to:Sung-Ho Jung
Tel 82-2-3010-3580
Fax 82-2-3010-6966
E-mail csjung@amc.seoul.kr
ORCID
https://orcid.org/0000-0002-3699-0312

Received: July 18, 2022; Revised: September 29, 2022; Accepted: October 1, 2022

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although cardiac myxoma is one of the most common types of benign cardiac tumors, infected cardiac myxoma is very infrequent. The diagnosis of infected cardiac myxoma may be challenging because the presenting symptoms are non-specific and established management guidelines are lacking. This report describes a 39-year-old woman with a 5-month history of uncontrolled fever, chills, and myalgia who was diagnosed with myxoma and underwent mass excision. Although blood and urine cultures were negative for growing bacteria, a pathologic examination showed that the excised mass was a left atrial myxoma, with pan-bacterial polymerase chain reaction (PCR) of the surgical specimen revealing Haemophilus parainfluenzae at 99.87%, resulting in a diagnosis of infected cardiac myxoma. Laboratory tests, such as PCR, may supplement culture results in the diagnosis of infected cardiac myxoma.

Keywords: Infected cardiac myxoma, Haemophilus parainfluenzae, Case report

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